Angilock 100 Tablet

 

.Angilock 100

Tablet

Generics:Losartan Potassium 100mg

Square Pharmaceuticals Limited

price/11 tk

Symptoms of Angilock 100

Hypertension: Losartan Potassium is indicated for the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents (eg. thiazide diuretics).

Pharmacology

Losartan Potassium is the primary non-peptide orally dynamic angiotensin II receptor blocker. It ties to the AT1 receptor found in numerous tissues (e.g. vascular smooth muscle, adrenal organ, kidneys and the heart) and diminishes a few imperative natural activities counting vasoconstriction and the discharge of aldosterone dependable for hypertension.

Dosage

The usual starting and maintenance dose is 50 mg once daily for most patients. If the antihypertensive effect using 50 mg once daily is inadequate, 25 mg twice daily is recommended prior to increasing the dose. For patients with intravascular volume-depletion (e.g., those treated with high-dose diuretics), a starting dose of 25 mg once daily should be considered. Losartan Potassium can be administered once or twice daily. The total daily dose ranges from 25 mg to 100 mg.

Interaction of Angilock 100

Rifampicin and fluconazole decrease levels of dynamic metabolite of Losartan Potassium. Concomitant utilize of Losartan Potassium and hydrochlorothiazide may lead to potentiation of the antihypertensive impacts. Concomitant utilize of potassium-sparing diuretics (eg, spironolactone, triamterene, amiloride), potassium supplements or salt substitutes containing potassium may lead to increments in serum potassium. The antihypertensive impact of losartan may be weakened by the non-steroidal anti-inflammatory medicate indomethacin. The utilize of ACE-inhibitor, angiotensin receptor adversary, an anti-inflammatory medicate and a thiazide diuretic at the same time increments the chance of renal impedance.

 

Side Effects of Angilock 100

The side effects with the use of Losartan Potassium are mild and transient in nature. The most common side effects are dizziness, diarrhea, nasal congestion, cough, upper respiratory infection. Other side effects are fatigue, oedema, abdominal pain, chest pain, nausea, headache & pharyngitis.

Pregnancy & Lactation

Pregnancy Category D. The risk to the fetus increases if Losartan Potassium is administered during the second or third trimesters of pregnancy. It is not known whether Losartan Potassium is excreted in human milk, as many drugs are excreted in human milk and because of the potential for adverse effects on the nursing infant, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.

Warnings

Use of Losartan Potassium during the second and third trimesters of pregnancy reduces fetal renal function and increases fetal and neonatal morbidity and death. In patients who are intravascularly volume-depleted (e.g., those treated with high-dose diuretics), symptomatic hypotension may occur. 

Storage Conditions

keep in a dry place away from light and heat. Keep out of the reach of children.

Generic Name of Angilock 100

Losartan Potassium.

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